Ingano y'imiti ya Triglycerides (MCT) y'uruhererekane rw'imiti | Isosiyumu ya Lipophilic & Ifata imiti yo kunywa/guterwa mu kanwa/guterwa mu inshinge | USP/EP/ChP

Triglycerides yacu yo mu bwoko bwa Medium-Chain (MCT) ni umuti urimo triglycerides nyinshi zigizwe na aside irike ya caprylic (C8) na capric (C10), ikomoka ku mavuta ya kokonati n'ay'ibitoki.Igaragara nk'amazi meza, adafite ibara cyangwa umuhondo, afite amavuta make kandi afite impumuro n'uburyohe bidahinduka.MCT ikora nk'umusemburo mwiza cyane ku miti igabanya ubukana bw'ibinure, itwara imiti kugira ngo irusheho kuba nziza, igabanya ubukana bw'imiti ikoreshwa mu gusiga amavuta, ndetse ikanatuma uruhu rugera ku ruhu.Itanga ubushobozi bwo kudahinduka kw'uturemangingo, ifata neza cyane (izenguruka ry'umuyoboro w'amaraso nta myunyungugu), kandi ihuza neza na API n'ibindi bikoresho biyifasha mu gukora oxidative.Ihuye na USP-NF, EP, JP, na ChP pharmacopoeias hamwe na CDE registration F20220000316Ikwiriye imiti/udupira two kunywa, amavuta yo kwisiga, indyo yuzuye, hamwe n'uburyo bwo gutanga imiti bwikora (SEDDS).

Twandikire

Ibisobanuro birambuye ku gicuruzwa

Triglycerides zo mu rwego rwo hagati mu mikorere y'imiti (MCT)

Incamake y'ibicuruzwa

Triglycerides y'uruhererekane rw'imiti (MCT) ni umuti wemewe ugizwe n'uruvange rwa triglycerides ya aside y'ibinure byuzuye, cyane cyane aside caprilic (C8H16O2, aside octanoic) na aside capric (C10H20O2, aside decanoic)Izi triglycerides ziva mu mavuta adahinduka akurwa mu gice gikomeye kandi cyumye cy'intanga ngabo z'ikinyobwa (Cocos nucifera L.) cyangwa mu ntanga ngabo zumye z'intanga ngabo z'ikinyobwa (Elaeis guineensis Jacq.)Aside irike itandukanywa n'amavuta y'ibinure hanyuma ikongera gushyirwamo glycerol kugira ngo habeho umusaruro wa nyuma..

Indangamuntu y'igicuruzwa:

Izina ry'ibinyabutabire:Triglycerides zo mu bwoko bwa Medium Chain / Caprylic / Capric Triglyceride
Nimero ya CAS:73398-61-5 (nanone 85409-09-2 cyangwa 538-24-9)
Nomero yo kwiyandikisha ya CDE:F20220000316
Iyubahirizwa ry'amategeko agenga farumasi:ChP (CP2020), USP-NF (Triglycerides zo mu Muyoboro w'Uburinganire), EP (Triglycerides, Umuyoboro w'Uburinganire), JP (Triglyceride y'ibinure byo mu muyoboro w'Uburinganire bw'Uburinganire)
Amagambo asa:Amavuta ya MCT, Caprylic/Capric Triglyceride, Glycerides ivanze na decanoyl na octanoyl, Miglyol® 812 ingana, Labrafac™ CC ingana
Ishusho:Amavuta adafite ibara cyangwa umuhondo muto, nta mpumuro cyangwa uburyohe
Aho gukonjesha:Hafi 0°C

Ibintu by'ingenzi n'inyungu

1. Ibiranga imiterere y'ibinyabutabire by'ikirenga

Umusemburo mwiza cyane ku miti igabanya ubukana bw'ibinure n'ibinyabutabire bidashonga neza mu mazi
Yongera uburyo bwo gushonga no gutuza ibinyabutabire bya lipophilic
Binoza uburyo imiti yo mu cyiciro cya kabiri n'icya kane iboneka (BCS classification)

2. Kwinjira vuba no Guhindura umubiri

Ishyirwa mu nzira y'amaraso mu buryo butaziguye nta mpamvu yo gukoresha umunyu wa bile cyangwa enzymes za pancreas.
Ihinduka vuba kugira ngo itange ingufu vuba
Gutanga API vuba mu mikorere y'umubiri, bishobora gutuma ibikorwa bitangira neza

3. Imiterere myiza y'ihindagurika

Ubudahangarwa bwinshi ku isuku (agaciro ka iyode ≤1.0)
Ubushobozi buke bwo kurwara ubushyuhe n'ingufu za oxidative
Ibungabunga umutekano n'igihe ntarengwa cy'imiti
Ihamye mu bushyuhe bwinshi bwo kubika (ni ngombwa ko ≤25°C)

4. Imiterere myiza y'umubiri

Ubucucike:~30 mPa·s kuri 20°C (ubushyuhe buke kugira ngo byoroshye kuyikoresha)
Uburemere bwihariye:0.93-0.96 kuri 20°C
Igipimo cy'ikirahure:1.440-1.452 kuri 20°C
Ubushyuhe buke bukwiriye ubwoko bw'ibinini by'amazi n'ibinini bito

5. Guhuza neza cyane

Ihuye n'ubwoko bwinshi bwa API n'ibindi bikoresho by'imiti
Bishobora gushyirwa mu buryo bworoshye mu buryo butandukanye nta kibazo cyo guhuza
Impumuro n'uburyohe bidashingiye ku bipimo - ni byiza cyane mu kunywa aho uburyohe buhagije ari ingenzi

6. Imiterere y'amategeko n'umutekano