Carboxymethylcellulose Kalisiyumu (CMC-Ca) Superdisintegrant | Ubushobozi bwo kubyimba cyane bwo gushwanyagurika vuba kw'ibinini | USP/EP/ChP Compliant

Kalisiyumu yacu ya Carboxymethylcellulose (Carmellose Calcium, CMC-Ca) ni umuti ukoreshwa mu buvuzi bw’imiti ufite isuku nyinshi, ukora nk'umuti ugabanya, ufunga, kandi ugabanya ubukana bw’ibipimo bikomeye binyobwa.Ni umunyu wa kalisiyumu wa carboxymethylcellulose, ugaragara nk'ifu y'umweru kugeza ku yera idashongesha mu mazi ariko irushaho kwiyongera inshuro nyinshi iyo ihuye n'amazi.Ubu buryo budasanzwe bwo kubyimba butuma ibinini bishonga vuba kandi bikanatuma imiti ishonga neza. Ibyiza by'ingenzi birimo: kutagira sodium (ikwiriye abarwayi bafite indwara z'umutima n'imitsi idahagije), ubushobozi bwo gukanda neza, kandi bujyanye n'uburyo bwo gukanda buziguye ndetse n'uburyo bwo gukanda butose . Ihuye na farumasi ya USP-NF, EP, JP, na ChP hamwe n'inyandiko ya CDE F20230000328. Urwego rusanzwe rw'ikoreshwa: 0.5-15% w/w.

Twandikire

Ibisobanuro birambuye ku gicuruzwa

Kalisiyumu yo mu rwego rwa farumasi ya Carboxymethylcellulose (Carmellose Calcium, CMC-Ca)

Incamake y'ibicuruzwa

Carboxymethylcellulose Kalisiyumu ni umunyu wa kalisiyumu wa polycarboxymethyl ether ya seluloseNi umuti ukoreshwa mu buryo bwinshi mu miti, ukoreshwa cyane nk'umuti ugabanya ubukana, uvanga, kandi uvanga ibinini mu binini birimo ibinini na kapsule.Bitandukanye na sodium, umunyu wa kalisiyumu utanga akarusho ko gukora imvange idafite sodium, bigatuma ikwiriye cyane abarwayi b'umutima n'imitsi bafite ikibazo cy'umunyu n'amaraso..

Indangamuntu y'igicuruzwa:

Izina ry'ibinyabutabire:Karuboksimetiliselulose Kalisiyumu / Kalisiyumu ya Carmelose
Nimero ya CAS:9050-04-8
Nomero yo kwiyandikisha ya CDE:F20230000328
Iyubahirizwa ry'amategeko agenga farumasi:ChP, USP-NF, EP, JP
Amagambo asa:Kalisiyumu carboxymethylcellulose, Kalisiyumu CMC, CMC-Ca, Kalisiyumu ya Carmellose
BAMWE:UTY7PDF93L
Ishusho:Ifu y'umweru kuva ku muhondo kugeza ku mweru cyangwa umweru udasa n'umweru, ifite imiterere y'isuku nyuma yo kumisha
Gushonga:Mu by’ukuri ntishobora gushonga mu mazi, acetone, alcool na toluene; ibyimba mu mazi bigatuma ikora stop

Ibintu by'ingenzi n'inyungu

1. Uburyo bwo Gusenya Bukomeye

Amazi ntashonga ariko yiyongera vuba kugeza kuinshuro nyinshi ingano yayo y'umwimerereiyo ihuye n'amazi aturuka mu mazi
Bitera imbaraga z'imashini zigabanya vuba ibinini
Bituma imiti ishonga vuba kandi burundu kugira ngo ishobore gushonga neza
Ikora neza ndetse no mu binini bikomeye aho ibindi binyabutabire bishobora kudakora neza

2. Ikoreshwa ry'ibikoresho byinshi

Itandukaniro:Akamaro k'ibanze ko gutakaza ibinini ku kigero cya 0.5-15%
Icyuma gifunga:Uburyo bwo gufata neza ibintu mu mikorere y'ibumba ritose
Umuti ugabanya ubushyuhe/ugeraza:Ishobora gukoreshwa nk'umuti ugabanya ubukana bw'ibinini
Ubufasha bwo guhagarika impanuka:Ikoreshwa nk'ikintu gitera imbaraga mu kunywa no mu guteka ibiryo biri mu mubiri

3. Akamaro kadafite Sodiyumu

Nta sodium irimo - ni nziza ku miti y'umutima n'abarwayi bafite ikibazo cy'umunyu
Ikemura ikwirakwira ry’ibikenewe mu mategeko n’abarwayi ku birebana n’imisemburo irimo sodium nkeya
Ihuye n'uburyo bwo gutanga imiti isuku kandi ijyanye n'ubuzima

4. Guhuza neza cyane na API

By'umwihariko bigira ingaruka nziza kuriimiti ya sefalosporine, hamwe n'imiterere yagaragaye yo kunoza isesagurwa
Imiterere myiza ya chelating ifasha amatsinda amwe na amwe ya API
Ikorana n'ibintu byinshi bikora birimo: Pioglitazone HCl, Aminophylline, Berberine HCl, Milnacipran HCl, Cefixime, Nicorandil, n'ibindi byinshi

5. Imiterere myiza y'umubiri