Umurongo wo gukamura amazi mu bwoko bwa "Granulation Line" ufite ibipimo byinshi

Ikwiriye gukorwamo imiti ikomeye irimo uburozi bwinshi, ikora cyane, kandi itera allergie nyinshi, kandi igomba kugera ku bipimo bya OEB4 na OEB5 kugira ngo igabanye ibyago by'abayikora mu gihe cyo kuyikora ndetse n'ingaruka zayo ku bidukikije.

Ibikoresho byujuje amabwiriza ya GMP, GMP y’Uburayi, na FDA yo mu 2010 mu Bushinwa, kandi byujuje ibisabwa na OEB mu buryo butagira umwuka uva mu kirere, kugira ngo bigabanye kwangirika kw'ibicuruzwa ku bikoresho;

Amabwiriza ngenderwaho yerekeye EHS ku nganda z'imiti zo mu Bushinwa (2020); Imipaka yo Guhura n'Ibintu Bishobora Guteza Akaga mu Kazi

Shaka igiciro

ibisobanuro birambuye ku bicuruzwa

Umurongo wa Granulation w'ubwoko bwa Wet woroshye cyane ugizwe na 8

Ibiranga

1. Koresha agapfunyika k'umufuka w'umwuka, ugenzura umutekano;

2. Koresha agakapu ka PE cyangwa valve yo gushyiramo ibikoresho byo mu rugo kugira ngo ushyiremo ibikoresho byo mu rugo cyangwa upakurure;

3. Koresha sisitemu ya BIBO yo gusohora umwuka, hamwe na filter za F9/H13;

4. Gusukura WIP/Gusukura CIP/Gusukura hakoreshejwe intoki.

Ibisobanuro by'uburyo OEB ikoreshwa

API zifite uburozi bwa cytotoxicity n'ibikorwa byinshi ni ubwoko bw'ibinyabutabire by'imiti bifite imikorere myinshi mu buvuzi, bifite ingano nto y'ubuvuzi n'ingaruka nke, kandi byakuruye amasoko menshi mu myaka yashize. Nubwo isoko ry'imiti ikora cyane ari rinini, inahura n'imbogamizi zikomeye. Uretse kwica uturemangingo twa kanseri, imiti irwanya ibibyimba ishobora no kwica uturemangingo dusanzwe. Kubwibyo, ingaruka zayo zishobora gutera ubwivumbure ku bantu, kandi zangiza cyane ubuzima bw'abantu bazima. Kubwibyo, ingaruka nyamukuru zifatwa mu gukora API zifite uburozi bwa cytotoxic na active cyane ni uguhura n'umukungugu. Igisubizo cyiza ni ugukoresha ikoranabuhanga ryo kwitandukanya mu kirere kugira ngo hagenzurwe ingano y'umukungugu usohoka mu gikorwa cyo gukora. Kubera iyi miterere, uyu mushinga wiga ahanini ku gaciro ka OEL (Occupational Exposure Limit) ikoreshwa mu rwego rw'ibintu bikoresha uburozi bitandukanye, ndetse n'uburyo bwo guhumeka bwa OEB bukoreshwa mu bikoresho bijyana n'urwego rwo guhumeka. Dukurikije imiterere y'ibikoresho fatizo bifite uburozi bwa cytotoxic na active cyane, hashingiwe ku ikoranabuhanga risanzwe ryo kwifunga, ikoranabuhanga ryo kwifunga umuvuduko mubi n'ikoranabuhanga ryo kwitandukanya mu kirere, hakozwe ubushakashatsi ku buryo butandukanye bwo kwivanga bukwiriye ibikoresho nk'ibyo. Ikoranabuhanga ryo kuziba amazi mu buryo bwa micro-imyuka rishobora kuziba cyangwa kuziba bitewe n'uburozi bwinshi bwa cytotoxicity. Uburyo bwo kuzana amazi mu buryo bwa API bukoreshwa mu kugenzura igipimo cyo kuzana amazi mu buryo bwa micro-imyuka

Ibisabwa ku bikoresho bya OEB

1. OEB 1~2 ni ngombwa gushyiraho uburyo bwo guhumeka amazi mu gace runaka, nko guhumeka neza ahantu hagaragara.

2. OEB 3 Iyo habayeho gukorana n'umuntu ku kazi, ibikoresho n'ibikoresho bigomba gukoreshwa uko bishoboka kose, kandi ingamba zo kugenzura nko guhumeka, agapfundikizo k'amazi gakoreshwa mu buryo bwigenga gafite igikoresho cyo guhumeka cyo mu gace, agapfundikizo k'umukungugu, nibindi bigomba gukoreshwa mu bice by'umukungugu w'imiti bigaragara.

3. Urwego rwa OEB 4-5 Hagomba gushyirwa imbere ikoreshwa ry'ibikoresho n'ibikoresho bifunze byuzuye, hamwe n'igishushanyo mbonera cy'inzira z'ikoranabuhanga zifunze. Umurongo w'ibicuruzwa ugomba gukoresha ibikoresho n'ibikoresho byose bifunze. Hagomba gukoreshwa ingamba zo kugenzura nko gushyiramo ibikoresho mu mwanya wabyo, gukoresha agasanduku k'uturindantoki gafunze, valve ya α-β, kwinjira no gusohora agasanduku, nibindi. Ibikoresho bifunze bigomba gukoresha umwuka wabyo utagira umwuka mwinshi, nk'icyuma cyumisha ibintu bitatu muri kimwe.